Enzyme Engineering and Modification

Creative Enzymes provides the enzyme engineering and modification service to help clients with the increasing needs in improving enzyme activity and properties and creating the perfect biocatalyst for a new reaction. Creative Enzymes is one of the few companies that provide solutions to such challenging tasks. After many years in serving companies and research institutes, we have demonstrated high reliability of our services.

Q1: Why should I modify my enzyme?

The existing enzymes can go through certain structural alterations and hence, the resulted function and catalytic activity allow new catalyzed pathways of reactions. In addition, modification could also enhance biochemical properties, pharmacokinetics, and stability. Enzymes can be physically modified in immobilization and encapsulation. Researchers also extent naturally occurring chemical reactions of enzymes to other chemicals such as polymers, aldehydes, imidoesters and anhydrides, to give enzymes more divers properties. In addition, chemists have developed a large set of reactions that label the enzymes through post-expression modifications. Many properties of an enzyme may be modified to achieve the objective: