Allosteric Drug Discovery
Allosteric drug discovery focuses on identifying compounds that bind to non-active sites on proteins, modulating their function indirectly. This approach can offer greater specificity and fewer side effects compared to traditional drugs targeting active sites. By stabilizing or destabilizing specific protein conformations, allosteric modulators enhance or inhibit protein activity, presenting a promising strategy for treating various diseases. This method expands therapeutic options, particularly for proteins considered "undruggable" by conventional means. Visit: https://www.gaintherapeutics.c....om/perspectives/the-

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